Simvastatin

A medication used to treat high cholesterol and reduce the risk of cardiovascular disease including heart attacks and stroke.

What Simvastatin is Prescribed for

Simvastatin, also known as the brand name product Zocor, is a lipid-lowering drug derived synthetically from a fermentation product of _Aspergillus terreus_. It belongs to the statin class of medications, which are used to lower the risk of cardio...

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How Much Does Simvastatin Cost?

Depending on the pharmacy, Simvastatin prices will vary. Most people find Simvastatin extremely expensive.

For more information, see below for the specifics. Here are the costs of Simvastatin with and without insurance.

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Savings with CharityRx

CharityRx is here to help patients get the best price for Simvastatin. Each prescription filled helps us support charity organizations across the country. No matter where you live in the US, our Simvastatin coupon card is free for you!

CharityRx
CharityRx

No paperwork is required, no restrictions apply, and its confidential. We guarantee the lowest cost for Simvastatin without insurance! CharityRx was founded on the belief that access to healthcare should be a fundamental human right.

Through our program, everyone is eligible for pharmacy discounts, including tourists. With substantial discounts on thousands of FDA-approved medications, we pass the savings on to you.

Simvastatin details

Simvastatin, also known as the brand name product Zocor, is a lipid-lowering drug derived synthetically from a fermentation product of _Aspergillus terreus_. It belongs to the statin class of medications, which are used to lower the risk of cardiovascular disease and manage abnormal lipid levels by inhibiting the endogenous production of cholesterol in the liver. More specifically, statin medications competitively inhibit the enzyme hydroxymethylglutaryl-coenzyme A (HMG-CoA) Reductase, which catalyzes the conversion of HMG-CoA to mevalonic acid and is the third step in a sequence of metabolic reactions involved in the production of several compounds involved in lipid metabolism and transport including cholesterol, low-density lipoprotein (LDL) (sometimes referred to as "bad cholesterol"), and very low-density lipoprotein (VLDL). Prescribing of statin medications is considered standard practice following any cardiovascular events and for people with a moderate to high risk of development of CVD, such as those with Type 2 Diabetes. The clear evidence of the benefit of statin use coupled with very minimal side effects or long term effects has resulted in this class becoming one of the most widely prescribed medications in North America. Simvastatin and other drugs from the statin class of medications including , , , , and are considered first-line options for the treatment of dyslipidemia. Increasing use of the statin class of drugs is largely due to the fact that cardiovascular disease (CVD), which includes heart attack, atherosclerosis, angina, peripheral artery disease, and stroke, has become a leading cause of death in high-income countries and a major cause of morbidity around the world. Elevated cholesterol levels, and in particular, elevated low-density lipoprotein (LDL) levels, are an important risk factor for the development of CVD. Use of statins to target and reduce LDL levels has been shown in a number of landmark studies to significantly reduce the risk of development of CVD and all-cause mortality. Statins are considered a cost-effective treatment option for CVD due to their evidence of reducing all-cause mortality including fatal and non-fatal CVD as well as the need for surgical revascularization or angioplasty following a heart attack. Evidence has shown that even for low-risk individuals (with <10% risk of a major vascular event occurring within 5 years) statins cause a 20%-22% relative reduction in major cardiovascular events (heart attack, stroke, coronary revascularization, and coronary death) for every 1 mmol/L reduction in LDL without any significant side effects or risks. While all statin medications are considered equally effective from a clinical standpoint, is considered the most potent; doses of 10 to 40mg per day were found in clinical studies to result in a 45.8% to 54.6% decrease in LDL cholesterol levels, while simvastatin has been found to have an average decrease in LDL-C of ~35%. Potency is thought to correlate to tissue permeability as the more lipophilic statins such as simvastatin are thought to enter endothelial cells by passive diffusion, as opposed to hydrophilic statins such as and which are taken up into hepatocytes through OATP1B1 (organic anion transporter protein 1B1)-mediated transport. Despite these differences in potency, several trials have demonstrated only minimal differences in terms of clinical outcomes between statins.

Therapeutic Categories

Cytochrome P-450 CYP3A Inhibitors, Enzyme Inhibitors, Hydroxymethylglutaryl-CoA Reductase Inhibitors, Hypolipidemic Agents, Hypolipidemic Agents Indicated for Hyperlipidemia, Lipid Regulating Agents

Food Interactions

Avoid grapefruit products. Co-administration with grapefruit products may increase the risk for adverse effects such as myalgia.

Indications

Cardiovascular Events, Cardiovascular Event, Diabetes Mellitus, Heterozygous Familial Hypercholesterolemia, History of stroke or other cerebrovacular disease cardiovascular event, Mixed Hyperlipidemia, Hypercholesterolemia, Homozygous Familial Hypercholesterolemia, History of coronary heart disease cardiovascular event

How CharityRX Works

Giving is what we do. Savings, sharing, and seeking equity and wellness are our goals. With every prescription filled, we donate to a charity as part of our commitment to social responsibility.

Our discount cards help with Simvastatin cost while providing a positive impact on the lives of others.

  • Simple Process

    There are over 70,000 participating pharmacies and major chain stores that accept our discount prescription card. Maximize your savings by up to 80%!

    Simply present your CharityRx Card to your pharmacist and immediately save on the initial Simvastatin cost.

  • No Obligations

    Discounts on Simvastatin cost are easy to find with us. Once you find the right pharmacy you can download your free Simvastatin coupon with the click of a button.Data collection is not part of our service. The discount you receive does not require any personal information from you. Plus, it's 100% free.

  • Price Comparisons

    You can count on us to help you. We list all nearby pharmacies above, making it easy for you to choose the one that's right for you - or the lowest Simvastatin price near you.

    By using the 'drug price' search tool on our free App, you can compare prescription costs at pharmacies in your local area and save money.

  • Charitable

    While you save on Simvastatin cost prices - we give back to charities like: The Warrior Movement- Because every life matters. This organization holds the line in the battle against youth suicide.

    Project 150- Their goal is to provide support and services to homeless, displaced, and disadvantaged high school students so that they can stay in school, graduate, and achieve success.

    Wounded Warriors Project- We all share the duty and honor of supporting wounded veterans. In order to help them heal and transition back to civilian life, we pay tribute to their bravery and sacrifice.

Frequently Asked Questions

What is CharityRx?

CharityRx is the fastest-growing prescription discount card in America. Our mission is to make medications more affordable and give back to charities in need.

What are the eligibility criteria for getting a card?

There are no eligibility requirements for using a CharityRx card, it's free for everyone. No insurance is required.

Is CharityRx free to use?

Our card is free to download and use. Discounts are instantly applied at the pharmacy during checkout.

Where can I use my card

CharityRx is accepted in over 70,000 USA Pharmacies including Walgreens, CVS, Rite-Aid and Walmart.

How do I get a CharityRx card?

Download a card instantly to any computer or smartphone directly from our site.

Do I need medical insurance to use the card?

Our card is free for everyone. No Insurance is required.

Is CharityRx the same as healthcare insurance?

No. CharityRx is a prescription savings program and NOT healthcare insurance. You can use our card whether or not you have medical cover.

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